Publications

Receptor tyrosine kinases fall into distinct classes based on their inferred signaling networks

Wagner JP, Wolf-Yadlin A, Sevecka M, Grenier JK, Root DE, Lauffenburger DA, Macbeath G. Sci Signal. 2013 Jul 16;6(284):ra58. scisignal.2003994

A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models

Dai X, James RG, Habib T, Singh S, Jackson S, Khim S, Moon RT, Liggitt D, Wolf-Yadlin A, Buckner JH, Rawlings DJ. J Clin Invest. 2013 May 1;123(5):2024-36. Epub 2013 Apr 24.

A General Molecular Affinity Strategy for Global Detection and Proteomic Analysis of Lysine Methylation

Moore KE, Carlson SM, Camp ND, Cheung P, James RG, Chua KF, Wolf-Yadlin A, Gozani O. Mol Cell. 2013 May 9;50(3):444-56. Epub 2013 Apr 11. 

Quantitative proteomic analysis of HIV-1 infected CD4+ T cells reveals an early host response in important biological pathways: protein synthesis, cell proliferation, and T-cell activation

Navare ATSova PPurdy DEWeiss JM, Wolf-Yadlin A,  Korth MJChang STProll SCJahan TAKrasnoselsky ALPalermo REKatze MG"Quantitative proteomic analysis of HIV-1 infected CD4+ T cells reveals an early host response in important biological pathways: protein synthesis, cell proliferation, and T-cell activation". Virology. 2012 Jul 20;429(1):37-46. Epub 2012 Apr 26.

Lysate microarrays enable high-throughput, quantitative investigations of cellular signaling

Sevecka M, Wolf-Yadlin A, MacBeath G. “Lysate microarrays enable high-throughput, quantitative investigations of cellular signaling”. Mol Cell Proteomics. 2011 Apr;10(4):M110.005363. Epub 2011 Feb 4.

Maximum entropy reconstructions of dynamic signaling networks from quantitative proteomics data

Locasale JW, Wolf-Yadlin A. “Maximum entropy reconstructions of dynamic signaling networks from quantitative proteomics data”. PLoS One. 2009 Aug 26; 4(8):e6522. Pubmed

Dissecting Protein Function and Signaling Using Protein Microarrays

Wolf-Yadlin A, Sevecka M, MacBeath G. “Dissecting Protein Function and Signaling Using Protein Microarrays”. Curr. Opin. Chem. Biol. 2009; 13(4):398-405. Epub 2009 Aug 5.

Linear combinations of docking affinities explain quantitative differences in RTK signaling

Gordus A, Krall JA, Beyer EM, Kaushansky A,  Wolf-Yadlin A, Sevecka M, Chang BH, Rush J, MacBeath G. “Linear combinations of docking affinities explain quantitative differences in RTK signaling”. Mol Syst Biol. 2009; 5:235. Epub 2009 Jan 20.

 

Quantitative Proteomic Analysis of Phosphotyrosine-Mediated Cellular Signaling Networks

Zhang Y, Wolf-Yadlin A, White FM. “Quantitative Proteomic Analysis of Phosphotyrosine-Mediated Cellular Signaling Networks”. Methods Mol Biol. 2007; 359(14):203-212.

 

Multiple Reaction Monitoring for Robust Quantitative Proteomic Analysis of Cellular Signaling Networks

Wolf-Yadlin A, Hautaniemi S, Lauffenburger DA, White FM. “Multiple Reaction Monitoring for Robust Quantitative Proteomic Analysis of Cellular Signaling Networks”. Proc Natl Acad Sci U S A. 2007; 104(14):5860-5. Epub 2007 Mar 26. 

 
Publication document:

Modeling HER2 effects on cell behavior from mass spectrometry phosphotyrosine data.

Kumar N, Wolf-Yadlin A, White FMLauffenburger DA. "Modeling HER2 effects on cell behavior from mass spectrometry phosphotyrosine data.

"PLoS Comput Biol. 2007 Jan 5;3(1):e4. Epub 2006 Nov 21.

Effects of HER2 overexpression on cell signaling networks governing proliferation and migration

Wolf-Yadlin AKumar NZhang YHautaniemi SZaman MKim HDGrantcharova VLauffenburger DAWhite FM. "Effects of HER2 overexpression on cell signaling networks governing proliferation and migration". Mol Syst Biol. 2006;2:54. Epub 2006 Oct 3.

Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules

Zhang Y, Wolf-Yadlin A, Ross PLPappin DJRush JLauffenburger DAWhite FM. "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules." Mol Cell Proteomics. 2005 Sep;4(9):1240-50. Epub 2005 Jun 11.